Cyproterone is used to treat cancer of the prostate gland. The prostate gland is present only in males; therefore, females do not get prostate cancer.
Blood clots (or history of) or
Circulation disease (or history of) or
Stroke (or history of)—If these conditions are already present, cyproterone may have a greater chance of causing blood clotting problems.
Cardiac disease— May causes the condition worse.
Depressive tendencies—May causes depression to occur.
Type 2 diabetes mellitus—May causes a loss of control of diabetes by increasing blood and urine sugar.
Liver disease—Effects of cyproterone may be increased because of its slower removal from the body.
The dose of cyproterone will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of cyproterone. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (tablets):
For treating prostate cancer:
Adults—100 to 200 milligrams (mg) per day divided into 2 to 3 doses. Take after meals.
For injection dosage form:
For treating prostate cancer:
Adult—300 milligrams (mg) injected into a muscle once a week.
Cyproterone belongs to a group of medications known as steroidal antiandrogens. It is used to treat advanced prostate cancer. Antiandrogens such as cyproterone block the effect of the hormone called testosterone. This causes a reduction in the production of testosterone in the testicles, which prostate cancer cells require for growth.
It is very important that your doctor checks your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
cyproterone may cause some people to become drowsy, dizzy, or less alert than they are normal. Make sure you know how you react to cyproterone before you drive, use machines or do anything else that could be dangerous if you are dizzy or are not alert.
Cyproterone may cause your skin to be more sensitive to sunlight than it is normal. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking cyproterone:
Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat. Also, wear sunglasses.
Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your healthcare professional.
Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
Do not use a sunlamp or tanning bed or booth.
If you have a severe reaction from the sun, check with your doctor.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur: Abdominal pain or tenderness;agitation; back pain; black, tarry stools; blisters on the skin; bloody urine; blurred vision chest pain;chills; clay-colored stools; confusion; cough; dark urine; decreased appetite; decreased urine output; difficulty swallowing; dilated neck veins; dizziness; drowsiness; dry mouth; fainting or light-headedness when getting up from a lying or sitting position suddenly; fast heartbeat; fatigue; fever; flushed, dry skin; fruit-like breath odor; general feeling of discomfort or illness; hallucinations; headache, sudden and severe; hives; inability to speak; increased blood pressure; increased hunger; increased thirst; increased urination; irregular breathing; irregular heartbeat; itching; loss of consciousness; lower back or side pain; mood or mental changes; nausea and vomiting; painful or difficult urination; pains in the chest, groin, or legs, especially the calves of legs; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue, thickened, or scaly skin; seizures; shortness of breath; skin rash; slurred speech; sore throat; sores, ulcers, or white spots on the lips or in the mouth; stiff neck; stomachache; sudden loss of coordination; sweating; swelling of the feet or lower legs; swollen and/or painful glands; temporary blindness; tightness in the chest; unexplained weight loss; unusual bleeding or bruising; vision changes; weakness in the arm and/or leg on one side of the body, sudden and severe; wheezing; yellow eyes or skin.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Decreased interest in sexual intercourse
inability to have or keep an erection
the increase in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
the loss in sexual ability, desire, drive, or performance
swelling of the breasts or breast soreness in both females and males
unexpected or excess milk flow from breasts
If an overdose situation happens seek emergency help.