Pancreatin Caps

Pancreatin Caps 20 caps x 0.15 (10000 UA)
Substance

Packing:

Each box contains 20 caps.

Composition:

A caps contains 0.15 (10000 UA) of Pancreatin

Indications:

Pancreatin is used to replace digestive enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, such as cystic fibrosis, pancreatitis, pancreatic cancer, or pancreas surgery.

Pancreatin may also be used to treat a condition called steatorrhea (loose, fatty stools).



Contra - indications:

You should not take pancreatin if you are allergic to pork proteins, or if you have a sudden onset of pancreatitis or worsening of a long-term problem with your pancreas.

To make sure pancreatin is safe for you, tell your doctor if you have:

  • gout;

  • asthma; or

  • any allergies.

FDA pregnancy category C. It is not known whether pancreatin will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

It is not known whether pancreatin passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.



Administration:

For helping digestion when the pancreas has been removed or isn't functioning properly (pancreatic insufficiency): the starting dose of pancreatin is usually 8,000 to 24,000 USP units of lipase activity taken before or with each meal or snack. Lipase is one of the chemicals contained in pancreatin that helps with digestion. To control fatty stools that are sometimes associated with pancreatic insufficiency, the dose can be increased as needed or until nausea, vomiting, or diarrhea occurs. These side effects of treatment indicate that the highest tolerable dose has been reached. Pancreatin is available as tablets that are treated to resist breakdown by stomach acids (enteric-coated), powder, or capsules containing the powder or enteric-coated granules.

Note that each mg of pancreatin contains at least 25 USP units of amylase activity, 2 USP units of lipase activity, and 25 USP units of protease activity. Pancreatin that is stronger is labeled as a multiple of these three minimum activities, e.g., pancreatin 4X. .



Medical action:

Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase, and protease. This mixture is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer and cystic fibrosis weight loss. Pancreatin is sometimes called "pancreatic acid", although it is neither a single chemical substance nor an acid.

Pancreatin contains the pancreatic enzymes trypsin, amylase, and lipase. A similar mixture of enzymes is sold as pancrelipase, which contains more active lipase enzyme than does pancreatin. The trypsin found in pancreatin works to hydrolyze proteins into oligopeptides; amylase hydrolyzes starches into oligosaccharides and the disaccharide maltose, and lipase hydrolyzes triglycerides into fatty acids and glycerols. Pancreatin is an effective enzyme supplement for replacing missing pancreatic enzymes, and aids in the digestion of foods in cases of pancreatic insufficiency.

Pancreatin reduces the absorption of iron from food in the duodenum during digestion



Precautions:

Hypersensitivity to Pork

Use with extreme caution, if at all, in patients with known hypersensitivity to pork products.100 101 a (See Contraindications.)

If hypersensitivity occurs, discontinue pancreatin and treat symptoms.100 101

Other Hypersensitivity Reactions

Patients may experience allergic reactions if capsules are opened and the powder accidentally inhaled; inhalation of airborne powder may precipitate an asthmatic attack in sensitive individuals.100 101

Other hypersensitivity reactions (e.g., sneezing, lacrimation, rash) may occur.a



Side effects:

Irritation of mucous membranes and respiratory tract,100 101 diarrhea or other transient intestinal upset (with excessive dosage), a hyperuricosuria and hyperuricemia (with extremely high doses).a



Overdosage:

If an overdose situation happens seek emergency help.