Testosterone U

Testosterone U 1 amps x 4 ml
Substance

Indications:

Testosterone undecanoate is used to treat low testosterone in men when the body is not producing any testosterone or not enough testosterone (hypogonadism).



Contraindications:

The drug should not be used in any of these patients:

Men with carcinoma of the breast or suspected carcinoma of the prostate.

Women that are pregnant or intend to be, or who are breastfeeding a newborn baby. Testosterone U can cause fetal harm when administered to a pregnant woman. This medicine can induce adverse reactions in a nursing baby. The impact of testosterone U on a fetus or nursing infant may result in different degrees of virilization. Men with hypersensitivity to testosterone undecanoate.



Administration:

Testosterone U is for intramuscular use. Titration is not necessary. The injection of testosterone u should be done deeply into the gluteal muscle; care must be taken to avoid intravascular injection. Intravascular injection of testosterone undecanoate may induce the pulmonary oil micro embolism.

The optimal dose of testosterone undecanoate is 3 ml (750 mg) injected intramuscularly, followed by 3 ml (750 mg) injected after 4 weeks, then 3 ml (750 mg) injected every 10 weeks thereafter.



Medical action:

Endogenous androgens keep the normal function, growth, and development of the male sex organs and for maintenance of secondary sex characteristics, growth and maturation of prostate, seminal vesicles, penis, and scrotum; the development of male hair distribution, such as facial, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body musculature and fat distribution.

Male hypogonadism, a disease caused by insufficient secretion of testosterone, that has two etiologies. Primary hypogonadism is resulted from defects of the gonads, such as Klinefelter’s syndrome or Leydig cell aplasia, whereas secondary hypogonadism is the injury of the hypothalamus (or pituitary) to produce sufficient gonadotropins (FSH, LH).

Precautions:

There are medicines that may interact with testosterone undecanoate. Announce your doctor or pharmacist if you have any of the following medical conditions:

  • if you are pregnant, intend to become pregnant, or are breastfeeding

  • if you are taking any medicines, herbal preparation, or dietary supplement

  • if you are allergic to medicines, foods, or other substances

  • if you have heart problems, kidney or liver problems, an enlarged prostate gland, high cholesterol levels, swelling (edema) or problems retaining fluid, lung problems, cancer, high blood calcium levels, diabetes, or sleep apnea.

  • f you are very overweight

  • if you have a history of blood clots

Side effects:

Call your doctor if any of these most general side effects continue: Acne; change in sex drive; emotional ups and downs; pain at the injection site; tiredness; trouble sleeping.

Call for medical help right away if any of these serious side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the size or shape of the testicles; changes in skin color; decreased sex ability; enlarged or painful breasts; erections that happen often or that last a long time; long pauses in breathing while you sleep; mood changes; swelling of the hands, ankles, or feet; symptoms of blood clots (eg, calf or leg pain, swelling, redness, or tenderness; chest pain; coughing up blood; shortness of breath); symptoms of liver problems (eg, dark urine; loss of appetite; pale stools; right-sided stomach pain; unusual nausea, vomiting, or tiredness; yellowing of the skin or eyes); urination problems (eg, feeling the need to pass urine right away, having a urine accident, passing urine more at night, passing urine often during the day, trouble starting the urine stream, weak urine stream); weight gain.



Overdosage:

Call the emergency if you took an overdose of testosterone undecanoate.