Methandienone is administrated in the treatment of severe cachexia resulting from AIDS, severe illness or unexplained medical reasons. Methandienone can be used for the treatment of hereditary angioedema.
Hypersensitivity to the drug, prostate cancer, breast cancer in men, breast carcinoma in women with hypercalcemia, CPI, severe atherosclerosis, hepatic and renal function, acute and chronic prostatitis, pregnancy and lactation.
Methandienone comes as a tablet containing 10 mg Methandienone, administrated orally. As the half time of methandienone, 10mg is only 3.2 to 4.5 hours, taking it, at least, two times a day is necessary to have an optimal concentration of methandienone in the blood. In order to avoid possible gastrointestinal pain, it is recommended to administrate the pills during the meals.
Methandienone is an anabolic steroid. Affecting the cell nucleus, activates the genetic apparatus of the cell, causing a large synthesis of DNA, RNA, and structural proteins, stimulates the enzymes of tissue respiration chain and enhancing tissue respiration, oxidative phosphorylation, ATP synthesis and intracellular macroergic aggregation. Activates anabolic and inhibits catabolic processes those activated by glucocorticoids. Contributes to an increased muscle mass, minimizes fat deposits, stimulates trophic tissues, improves calcium deposits in the bones, retain nitrogen, phosphorus, sulfur, potassium, sodium and water in the body. The action is the enhancement of hematopoietic erythropoietin synthesis.
Women are not indicated to use methandienone because high virilization symptoms can occur. Methandienone 10mg has many potential side effects, they are low at a dosage of up to 20 mg per day. Methandienone 10mg causes a considerable strain on the liver and high dosages or use of over a longer period of time, is liver-toxic. Even a dosage of only 10 mg./day can increase the liver values but after discontinuation of the drug, however, the values return to normal. While using methandienone high blood pressure and a faster heartbeat can happen which may require the administration of an antihypertensive drug. Additional administration of Tamoxifen and Proviron may be necessary while Methandienone 10mg strongly converts into estrogens.
Methandienone can induce a serious acne on the face, neck, chest, back, and shoulders since the sebaceous gland function was stimulated. If a hereditary predisposition exists, Methandienone 10mg can also cause a possible hair loss. Methandienone since the water retained during the cycle is again excreted by the body. A high dosage may provoke aggressive behavior in the user which could be occasionally observed.
If in the case of an overdose of Methandienone is suspected, contact your doctor immediately.